The Desmoglein 3 Antibody / DSG3 from Biorbyt is a Mouse Monoclonal antibody to Desmoglein 3, and DSG3. This antibody recognizes Homo Sapiens, and Human antigen. The Desmoglein 3 Antibody / DSG3 has been validated for the following applications: Cell Sorting, Isolation, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily